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Hood, K. Y., Mair, K. M., Harvey, A. P., Montezano, A. C., Touyz, R. M. and MacLean, M. R. (2017) Serotonin signaling through the 5-HT1B receptor and NADPH oxidase 1 in pulmonary arterial hypertension. Arteriosclerosis, Thrombosis, and Vascular Biology, 37(7), pp. 1361-1370. (doi:10.1161/ATVBAHA.116.308929) (PMID:28473438) (PMCID:PMC5478178)

Hood, K. Y., Montezano, A. C., Harvey, A. P., Nilsen, M., MacLean, M. R. and Touyz, R. M. (2016) Nicotinamide adenine dinucleotide phosphate oxidase–mediated redox signaling and vascular remodeling by 16α-hydroxyestrone in human pulmonary artery cells. Hypertension, 68(3), pp. 796-808. (doi:10.1161/HYPERTENSIONAHA.116.07668) (PMID:27402919) (PMCID:PMC4978604)

Dean, A., Nilsen, M., Loughlin, L., Salt, I. P. and MacLean, M. R. (2016) Metformin reverses development of pulmonary hypertension via aromatase inhibition. Hypertension, 68(2), pp. 446-454. (doi:10.1161/HYPERTENSIONAHA.116.07353) (PMID:27296990)

Johansen, A. K. Z., Dean, A., Morecroft, I., Hood, K., Nilsen, M., Loughlin, L., Anagnostopoulou, A., Touyz, R. M. , White, K. and MacLean, M. R. (2016) The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation. Pulmonary Circulation, 6(1), pp. 82-92. (doi:10.1086/685023) (PMID:27162617) (PMCID:PMC4860551)

Wallace, E. , Morrell, N. W., Yang, X. D., Long, L., Stevens, H., Nilsen, M., Loughlin, L., Mair, K. M., Baker, A. H. and MacLean, M. R. (2015) A sex-specific microRNA-96/5HT1B Axis influences development of pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 191(12), pp. 1432-1442. (doi:10.1164/rccm.201412-2148OC) (PMID:25871906) (PMCID:PMC4476563)

Wright, A. F., Ewart, M.-A., Mair, K., Nilsen, M., Dempsie, Y., Loughlin, L. and MacLean, M. R. (2015) Oestrogen receptor alpha in pulmonary hypertension. Cardiovascular Research, 106(2), pp. 206-216. (doi:10.1093/cvr/cvv106) (PMID:25765937) (PMCID:PMC4615797)

Mair, K., Yang, X. D., Long, L., White, K., Wallace, E. , Ewart, M.-A., Docherty, C., Morrell, N. W. and MacLean, M. (2015) Sex affects bone morphogenetic protein type II receptor signaling in pulmonary artery smooth muscle cells. American Journal of Respiratory and Critical Care Medicine, 191(6), pp. 693-703. (doi:10.1164/rccm.201410-1802OC) (PMID:25608111) (PMCID:PMC4384779)

Mair, K. M. et al. (2014) Sex-dependent influence of endogenous estrogen in pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine, 190(4), pp. 456-467. (doi:10.1164/rccm.201403-0483OC) (PMID:24956156) (PMCID:PMC4214128)

Mair, K.M., Johansen, A.K.Z., Wright, A.F., Wallace, E. and MacLean, M.R. (2014) Pulmonary arterial hypertension: basis of sex differences in incidence and treatment response. British Journal of Pharmacology, 1(3), pp. 567-579. (doi:10.1111/bph.12281)

Dempsie, Y. and Maclean, M. R. (2013) The influence of gender on the development of pulmonary arterial hypertension. Experimental Physiology, 98, pp. 1257-1261. (doi:10.1113/expphysiol.2012.069120)

Dempsie, Y., MacRitchie, N.A., White, K., Morecroft, I., Wright, A.F., Nilsen, M., Loughlin, L., Mair, K.M. and MacLean, M.R. (2013) Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. Cardiovascular Research, 99(1), pp. 24-34. (doi:10.1093/cvr/cvt064) (PMID:23519266) (PMCID:PMC3687748)

Austin, E. D., Johansen, A. K., Alzoubi, A., Lahm, T., West, J., Tofovic, S. P., MacLean, M. R. and Oka, M. (2013) Gender, sex hormones and pulmonary hypertension. Pulmonary Circulation, 3(2), pp. 294-314. (doi:10.4103/2045-8932.114756) (PMID:24015330) (PMCID:PMC3757824)

Ciuclan, L. et al. (2013) Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression. American Journal of Respiratory and Critical Care Medicine, 187(1), pp. 78-89. (doi:10.1164/rccm.201206-1028OC)

Baranowska-Kuczko, M., MacLean, M. R., Kozłowska, H. and Malinowska, B. (2012) Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery. Pharmacological Research, 66(3), pp. 251-259. (doi:10.1016/j.phrs.2012.05.004)

McDonald, R. A., Hata, A., MacLean, M. R., Morrell, N. W. and Baker, A. H. (2012) MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling. Cardiovascular Research, 93(4), pp. 594-604. (doi:10.1093/cvr/cvr299)

White, K. et al. (2012) Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension. Circulation, 126(9), pp. 1087-1098. (doi:10.1161/CIRCULATIONAHA.111.062927)

Dempsie, Y., Nilsen, M., White, K., Mair, K., Loughlin, L., Ambartsumian, N., Rabinovitch, M. and MacLean, M. (2011) Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females. Respiratory Research, 12(1), p. 159. (doi:10.1186/1465-9921-12-159)

White, K., Loughlin, L., Maqbool, Z., Nilsen, M., McClure, J. , Dempsie, Y., Baker, A. H. and MacLean, M. R. (2011) Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH. Physiological Genomics, 43(8), pp. 417-437. (doi:10.1152/physiolgenomics.00249.2010)

White, K., Dempsie, Y., Nilsen, M., Wright, A. F., Loughlin, L. and MacLean, M. R. (2011) The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension. Cardiovascular Research, 90(2), pp. 373-382. (doi:10.1093/cvr/cvq408)

This list was generated on Sun Dec 8 03:22:22 2019 GMT.