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Parnell, E., Palmer, T. M. and Yarwood, S. J. (2015) The future of EPAC-targeted therapeutics: agonism versus antagonism. Trends in Pharmacological Sciences, 36(4), pp. 203-214. (doi:10.1016/j.tips.2015.02.003) (PMID:25744542) (PMCID:PMC4392396)

Wiejak, J., Tsimbouri, P. M. , Herzyk, P. , Dalby, M. J. , Hamilton, G. and Yarwood, S. J. (2013) Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves. Biomaterials, 34(8), pp. 1967-1979. (doi:10.1016/j.biomaterials.2012.11.036) (PMID:23245923) (PMCID:PMC3543902)

Wiejak, J., Dunlop, J. , Stoyle, C., Lappin, G., McIlroy, A., Pediani, J. D. , Gao, S. and Yarwood, S. J. (2012) The protein kinase C inhibitor, Ro-31-7459, is a potent activator of ERK and JNK MAP kinases in HUVECs and yet inhibits cyclic AMP-stimulated SOCS-3 gene induction through inactivation of the transcription factor c-Jun. Cellular Signalling, 24(8), pp. 1690-1699. (doi:10.1016/j.cellsig.2012.04.016)

Parnell, E., Smith, B. O. , Palmer, T. M., Terrin, A., Zaccolo, M. and Yarwood, S. J. (2012) Regulation of the inflammatory response of vascular endothelial cells by EPAC1. British Journal of Pharmacology, 166(2), pp. 434-446. (doi:10.1111/j.1476-5381.2011.01808.x)

Wiejak, J., Dunlop, J. , Gao, S., Borland, G. and Yarwood, S. J. (2012) Extracellular signal-regulated kinase mitogen-activated protein kinase-dependent SOCS-3 gene induction requires c-Jun, signal transducer and activator of transcription 3, and specificity protein 3 transcription factors. Molecular Pharmacology, 81(5), pp. 657-668. (doi:10.1124/mol.111.076976)

Milne, G. R., Palmer, T. M. and Yarwood, S. J. (2012) Novel control of cAMP-regulated transcription in vascular endothelial cells. Biochemical Society Transactions, 40(1), pp. 1-5. (doi:10.1042/BST20110606)

Williams, J. J.L. and Palmer, T. M. (2012) Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3. Biochemical Society Transactions, 40(1), pp. 215-218. (doi:10.1042/BST20110629)

Sands, W. A., Woolson, H. D., Yarwood, S. J. and Palmer, T. M. (2012) Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter. Methods in Molecular Biology, 809, pp. 201-214. (doi:10.1007/978-1-61779-376-9_14)

Milne, G. and Palmer, T. M. (2011) Anti-inflammatory and immunosuppressive effects of the A2A adenosine receptor. Scientific World Journal, 11, pp. 320-339. (doi:10.1100/tsw.2011.22)

Safhi, M. M. A., Rutherford, C., Ledent, C., Sands, W. A. and Palmer, T. M. (2010) Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A2a adenosine receptor. Molecular Pharmacology, 77(6), pp. 968-978. (doi:10.1124/mol.109.062455)

Mundell, S.J., Matharu, A.-L., Palmer, T.M., Benovic, J.L. and Kelly, E. (2010) Deletion of the distal COOH-terminus of the A2B adenosine receptor switches agonist-induced internalisation to an arrestin- and clathrin-independent pathway and inhibits receptor recycling. British Journal of Pharmacology, 159(3), pp. 518-533. (doi:10.1111/j.1476-5381.2009.00598.x)

Woolson, H. D., Thomson, V. S., Rutherford, C., Yarwood, S. J. and Palmer, T. M. (2009) Selective inhibition of cytokine-activated extracellular signal-regulated kinase by cyclic amp via Epac1-dependent induction of suppressor of cytokine signalling-3. Cellular Signalling, 21(11), pp. 1706-1715. (doi:10.1016/j.cellsig.2009.07.009)

Borland, G., Bird, R. J., Palmer, T. M. and Yarwood, S. J. (2009) Activation of protein kinase Cα by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein β-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells. Journal of Biological Chemistry, 284(26), pp. 17391-17403. (doi:10.1074/jbc.M109.015370)

This list was generated on Tue Dec 10 00:08:03 2019 GMT.