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Newman, J. P.A. et al. (2012) Erratum: Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells. Journal of Cellular Physiology, 227(7), p. 2972. (doi:10.1002/jcp.23064)

Chen, M. J. et al. (2011) Gene profiling reveals hydrogen sulphide recruits death signaling via the N-methyl-D-aspartate receptor identifying commonalities with excitotoxicity. Journal of Cellular Physiology, 226(5), pp. 1308-1322. (doi:10.1002/jcp.22459)

He, X., H'ng, S.-C., Leong, D. T., Hutmacher, D. W. and Melendez Romero, A. J. (2010) Sphingosine-1-Phosphate Mediates Proliferation Maintaining the Multipotency of Human Adult Bone Marrow and Adipose Tissue-derived Stem Cells. Journal of Molecular Cell Biology, 2(4), pp. 199-208. (doi:10.1093/jmcb/mjq011)

Puneet, P., Yap, C. T., Wong, L., Yulin, L., Koh, D. R., Moochhala, S., Pfeilschifter, J., Huwiler, A. and Melendez Romero, A. J. (2010) SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. Science, 328(5983), pp. 1290-1294. (doi:10.1126/science.1188635)

Hegde, A., Tamizhselvi, R., Manikandan, J., Melendez, A. J., Moochhala, S. M. and Bhatia, M. (2010) Substance P in polymicrobial sepsis: molecular fingerprint of lung injury in preprotachykinin-A–/– mice. Molecular Medicine, 16(5-6), pp. 188-198. (doi:10.2119/molmed.2009.00166)

Hueber, A. J., Asquith, D. L., Miller, A. M., Reilly, J., Kerr, S., Leipe, J., Melendez Romero, A. J. and McInnes, I. B. (2010) Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium. Journal of Immunology, 184(7), pp. 3336-3340. (doi:10.4049/jimmunol.0903566) (PMID:20200272)

Xu, D. et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184(5), pp. 2620-2626. (doi:10.4049/jimmunol.0902685) (PMID:20139274)

Harnett, M. M. , Melendez, A. J. and Harnett, W. (2010) The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease. Clinical and Experimental Immunology, 159(3), pp. 256-267. (doi:10.1111/j.1365-2249.2009.04064.x)

Choy, M. S., Chen, M. J., Manikandan, J., Peng, Z. F., Jenner, A. M., Melendez Romero, A. J. and Cheung, N. S. (2010) Up-regulation of endoplasmic reticulum stress-related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin. Journal of Cellular Physiology, 226(2), pp. 494-510. (doi:10.1002/jcp.22359)

Jayapal, M., Bhattacharjee, R. N., Melendez Romero, A. J. and Hande, M.P. (2010) Environmental toxicogenomics: a post-genomic approach to analysing biological responses to environmental toxins. International Journal of Biochemistry and Cell Biology, 42(2), pp. 230-240. (doi:10.1016/j.biocel.2009.10.007)

Sethu, S. and Melendez Romero, A. J. (2010) New developments on the TNFα-mediated signalling pathways. Bioscience Reports, 31(1), pp. 63-76. (doi:10.1042/BSR20100040)

Sethu, S., Pushparaj, P. N. and Melendez Romero, A. J. (2010) Phospholipase D1 mediates TNFα-induced inflammation in a murine model of TNFα-induced peritonitis. PLoS ONE, 5(5), e10506. (doi:10.1371/journal.pone.0010506)

Yap, Y.W., Chen, M.J., Choy, M.S., Peng, Z.F., Whiteman, M., Manikandan, J., Melendez Romero, A.J. and Cheung, N.S. (2010) Temporal transcriptomic profiling reveals cellular targets that govern survival in HOCl-mediated neuronal apoptosis. Life Sciences, 87(15-16), pp. 457-467. (doi:10.1016/j.lfs.2010.08.011)

Lai, W.-Q., Irwan, A. W., Goh, H. H., Melendez, A. J., McInnes, I. B. and Leung, B. P. (2009) Distinct roles of sphingosine kinase 1 and 2 in murine collagen-induced arthritis. Journal of Immunology, 183(3), pp. 2097-2103. (doi:10.4049/jimmunol.0804376) (PMID:19596980)

Issuree, P. D. A., Pushparaj, P. N., Pervaiz, S. and Melendez, A. J. (2009) Resveratrol attenuates C5a-induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities. FASEB Journal, 23(8), pp. 2412-2424. (doi:10.1096/fj.09-130542)

Pushparaj, P. N., Tay, H. K., Wang, C.-C., Hong, W. and Melendez, A. J. (2009) VAMP8 Is Essential in Anaphylatoxin-Induced Degranulation, TNF-alpha Secretion, Peritonitis, and Systemic Inflammation. Journal of Immunology, 183(2), pp. 1413-1418. (doi:10.4049/jimmunol.0804061)

Dai, X. et al. (2009) Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcγRI versus FcγRIIa. Blood, 114(2), pp. 318-327. (doi:10.1182/blood-2008-10-184457)

Dai, X. et al. (2009) Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcγRI versus FcγRIIa. Blood, 114(2), pp. 318-327. (doi:10.1182/blood-2008-10-184457)

Wong, L., Tan, S. S.L., Lam, Y. and Melendez, A. J. (2009) Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases. Journal of Medicinal Chemistry, 52(12), pp. 3618-3626. (doi:10.1021/jm900121d)

Pushparaj, P. N., Tay, H. K., H'Ng, S. C., Pitman, N., Xu, D., McKenzie, A., Liew, F. Y. and Melendez, A. J. (2009) The cytokine interleukin-33 mediates anaphylactic shock. Proceedings of the National Academy of Sciences of the United States of America, 106(24), pp. 9773-9778. (doi:10.1073/pnas.0901206106)

Lai, W.-Q., Irwan, A. W., Goh, H. H., Howe, H. S., Yu, D. T., Valle-Onate, R., McInnes, I. B. , Melendez, A. J. and Leung, B. P. (2008) Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis. Journal of Immunology, 181(11), pp. 8010-8017. (doi:10.4049/jimmunol.181.11.8010) (PMID:19017993)

Melendez, A. J. (2008) Allergy therapy: the therapeutic potential of targeting sphingosine kinase signalling in mast cells. European Journal of Immunology, 38(11), pp. 2969-2974. (doi:10.1002/eji.200838642)

Melendez, A. J. and Tay, H. K. (2008) Phagocytosis: a repertoire of receptors and Ca2+ as a key second messenger. Bioscience Reports, 28(5), pp. 287-298. (doi:10.1042/BSR20080082)

Chen, M. J., Sepramaniam, S., Armugam, A., Choy, M. S., Manikandan, J., Melendez, A. J., Jeyaseelan, K. and Cheung, N. S. (2008) Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system? Current Neuropharmacology, 6(2), pp. 102-116. (doi:10.2174/157015908784533879)

Sethu, S., Mendez-Corao, G. and Melendez, A. J. (2008) Phospholipase D1 plays a key role in TNF-α signaling. Journal of Immunology, 180(9), pp. 6027-6034.

Lai, W.-Q., Goh, H. H., Bao, Z., Wong, W. S. F., Melendez, A. J. and Leung, B. P. (2008) The role of sphingosine kinase in a murine model of allergic asthma. Journal of Immunology, 180(6), pp. 4323-4329.

Peng, Z. F., Chen, M. J., Yap, Y. W., Manikandan, J., Melendez, A. J., Choy, M. S., Moore, P. K. and Cheung, N. S. (2008) Proteasome inhibition: an early or late event in nitric oxide-induced neuronal death? Nitric Oxide, 18(2), pp. 136-145. (doi:10.1016/j.niox.2007.11.002)

Chi, Z. and Melendez, A. J. (2008) Role of cell adhesion molecules and immune-cell migration in the initiation, onset and development of atherosclerosis. Cell Adhesion and Migration, 1(4), pp. 171-175. (doi:10.4161/cam.1.4.5321)

Melendez, A. J. (2008) Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets. Biochimica et Biophysica Acta: Proteins and Proteomics, 1784(1), pp. 66-75. (doi:10.1016/j.bbapap.2007.07.013)

Melendez, A. J. and Mansoor, M. (2008) Recent trials for FTY720 (fingolimod): a new generation of immunomodulators structurally similar to sphingosine. Reviews on Recent Clinical Trials, 3(1), pp. 62-69. (doi:10.2174/157488708783330486)

Mansoor, M. and Melendez, A. J. (2008) Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics. Gene Regulation and Systems Biology, 2, pp. 275-295.

Pushparaj, P.N., H'ng, S.C. and Melendez Romero, A.J. (2008) Refining siRNA in vivo transfection: silencing SPHK1reveals its key role in C5a-induced inflammation in vivo. International Journal of Biochemistry and Cell Biology, 40(9), pp. 1817-1825. (doi:10.1016/j.biocel.2008.01.015)

Harnett, M. M. , Harnett, W., McSharry, C. P., Melendez, A. J., Pushparaj, P. N., Tay, H. K. and Wong, W. S. F. (2007) Inhibition of FcεRI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes. Nature Medicine, 13(11), pp. 1375-1381. (doi:10.1038/nm1654)

Cheung, N. S., Halliwell, B., Koh, C. H. V., Li, Q. T., Manikandan, J., Melendez, A. J., Peng, Z. F. and Tang, S. Y. (2007) Deciphering the mechanism of HNE-induced apoptosis in cultured murine cortical neurons: Transcriptional responses and cellular pathways. Neuropharmacology, 53(5), pp. 687-698. (doi:10.1016/j.neuropharm.2007.07.016)

Manikandan, J., Melendez, A. J. and Pushparaj, P. N. (2007) Protein i: interference at protein level by intrabodies. Frontiers in Bioscience, 12, pp. 1344-1352. (doi:10.2741/2152)

Chen, Y., Yuen, W. H., Fu, J., Huang, G., Melendez, A. J., Ibrahim, F. B. M., Lu, H. and Cao, X. (2007) The mitochondrial respiratory signaling and NFAT activity chain controls intracellular calcium essential for heart formation in Xenopus laevis. Molecular and Cellular Biology, 27(18), pp. 6420-6432. (doi:10.1128/MCB.01946-06)

Jayapal, M. and Melendez Romero, A.J. (2006) DNA microarray technology for target identification and validation. Clinical and Experimental Pharmacology and Physiology, 33(05-Jun), pp. 496-503. (doi:10.1111/j.1440-1681.2006.04398.x)

Chow, K.K., Jayapal, M., Melendez Romero, A.J., Rauff, M., Reghunathan, R., Tay, H.K. and Zhi, L. (2006) Genome-wide gene expression profiling of human mast cells stimulated by IgE or Fc epsilon RI-aggregation reveals a complex network of genes involved in inflammatory responses. BMC Genomics, 7, (doi:10.1186/1471-2164-7-210)

Cao, T., Heng, B.C., Kemeny, D.M., Liu, H., Melendez Romero, A.J. and Ouyang, H.W. (2006) The immunogenicity and immunomodulatory function of osteogenic cells differentiated from mesenchymal stem cells. Journal of Immunology, 176(5), pp. 2864-2871.

Pushparaj, P.N. and Melendez Romero, A.J. (2006) Short interfering RNA (siRNA) as a novel therapeutic. Clinical and Experimental Pharmacology and Physiology, 33(5-6), pp. 504-510. (doi:10.1111/j.1440-1681.2006.04399.x)

Zhi, L., Leung, B.P. and Melendez Romero, A.J. (2006) Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFα in primary human monocytes. Journal of Cellular Physiology, 208(1), pp. 109-115. (doi:10.1002/jcp.20646)

This list was generated on Sun Dec 15 03:52:32 2019 GMT.