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McLuskey, K., Paterson, N. G., Bland, N. D., Isaacs, N. W. and Mottram, J. C. (2010) Crystal structure of leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor. Journal of Biological Chemistry, 285(50), pp. 39249-39259. (doi:10.1074/jbc.M110.156679)

Williams, R. A.M., Woods, K. L., Juliano, L., Mottram, J. C. and Coombs, G. H. (2009) Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major. Autophagy, 5(2), pp. 159-172. (doi:10.4161/auto.5.2.7328)

Eschenlauer, S. C. P., Faria, M. S., Morrison, L. S., Bland, N., Ribeiro-Gomes, F. L., DosReis, G. A., Coombs, G. H. , Lima, A. P. C. A. and Mottram, J. C. (2009) Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major. Cellular Microbiology, 11(1), pp. 106-120. (doi:10.1111/j.1462-5822.2008.01243.x)

Lanfranco, M. F. et al. (2008) Expression and substrate specificity of a recombinant cysteine proteinase B of Leishmania braziliensis. Molecular and Biochemical Parasitology, 161(2), pp. 91-100. (doi:10.1016/j.molbiopara.2008.06.005)

Besteiro, S., Tonn, D., Tetley, L., Coombs, G. H. and Mottram, J. C. (2008) The AP3 adaptor is involved in the transport of membrane proteins to acidocalcisomes of Leishmania. Journal of Cell Science, 121(5), pp. 561-570. (doi:10.1242/jcs.022574)

Ambit, A., Fasel, N., Coombs, G. and Mottram, J. (2008) An essential role for the Leishmania major metacaspase in cell cycle progression. Cell Death and Differentiation, 15(1), pp. 113-122. (doi:10.1038/sj.cdd.4402232)

Steert, K., El-Sayed, I., Van der Veken, P., Krishtal, A., Van Alsenoy, C., Westrop, G. D., Mottram, J. C. , Coombs, G. H., Augustyns, K. and Haemers, A. (2007) Dipeptidyl α-fluorovinyl Michael acceptors: Synthesis and activity against cysteine protease. Bioorganic and Medicinal Chemistry Letters, 17(23), pp. 6563-6566. (doi:10.1016/j.bmcl.2007.09.075)

Kanaji, S. et al. (2007) Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases. FEBS Letters, 581, pp. 4260-4264. (doi:10.1016/j.febslet.2007.07.072)

Besteiro, S., Williams, R. A.M., Coombs, G. H. and Mottram, J. C. (2007) Protein turnover and differentiation in Leishmania. International Journal for Parasitology, 37, pp. 1063-1075. (doi:10.1016/j.ijpara.2007.03.008)

Gonzalez, I. J., Desponds, C., Schaff, C., Mottram, J. C. and Fasel, N. (2007) Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity. International Journal for Parasitology, 37, pp. 161-172. (doi:10.1016/j.ijpara.2006.10.004)

Carlton, J. M. et al. (2007) Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science, 315(5809), pp. 207-212. (doi:10.1126/science.1132894)

Peacock, C.S. et al. (2007) Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nature Genetics, 39, pp. 839-847. (doi:10.1038/ng2053)

Denise, H., Poot, J., Jiménez, M., Ambit, A., Herrmann, D.C., Vermeulen, A.N., Coombs, G. H. and Mottram, J.C. (2006) Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5. BMC Molecular Biology, 7(42),

Besteiro, S., Coombs, G.H. and Mottram, J.C. (2006) The SNARE protein family of Leishmania major. BMC Genomics, 7(250),

Eschenlauer, S. C.P., Coombs, G. H. and Mottram, J. C. (2006) PFPI-like genes are expressed in Leishmania major but are pseudogenes in other Leishmania species. FEMS Microbiology Letters, 260(1), pp. 47-54. (doi:10.1111/j.1574-6968.2006.00303.x)

Smith, B.O., Picken, N.C., Westrop, G.D., Bromek, K., Mottram, J.C. and Coombs, G.H. (2006) The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors. Journal of Biological Chemistry, 281, pp. 5821-5828. (doi:10.1074/jbc.M510868200)

Denise, H., Poot, J., Jimenez, M., Ambit, A., Herrmann, D.C., Vermeulen, A.N., Coombs, G.H. and Mottram, J.C. (2006) Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5. BMC Molecular Biology, 7(42), (doi:10.1186/1471-2199-7-42)

Schaeffer, M., de Miranda, A., Mottram, J. and Coombs, G. (2006) Differentiation of Leishmania major is impaired by over-expression of pyroglutamyl peptidase I. Molecular and Biochemical Parasitology, 150, pp. 318-329. (doi:10.1016/j.molbiopara.2006.09.004)

Williams, R., Tetley, L., Mottram, J. and Coombs, G. (2006) Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. Molecular Microbiology, 61, pp. 655-674. (doi:10.1111/j.1365-2958.2006.05274.x)

Smith, B.O., Westrop, G.D., Mottram, J.C. and Coombs, G.H. (2006) Chemical shift assignments of Leishmania mexicana ICP, a novel cysteine peptidase inhibitor. Journal of Biomolecular NMR, 36, p. 7. (doi:10.1007/s10858-005-4739-8)

Helms, M., Ambit, A., Appleton, P., Tetley, L., Coombs, G. and Mottram, J. (2006) Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes. Journal of Cell Science, 119, pp. 1105-1117. (doi:10.1242/jcs.02809)

Besteiro, S., Williams, R., Morrison, L., Coombs, G. and Mottram, J. (2006) Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major. Journal of Biological Chemistry, 281, pp. 11384-11396. (doi:10.1074/jbc.M512307200)

Poot, J., Spreeuwenberg, K., Sanderson, S., Schijns, V., Mottram, J. , Coombs, G. and Vermeulen, A. (2006) Vaccination with a preparation based on recombinant cysteine peptidases and canine IL-12 does not protect dogs from infection with Leishmania infantum. Vaccine, 24, pp. 2460-2468. (doi:10.1016/j.vaccine.2005.12.039)

This list was generated on Mon Oct 21 01:11:41 2019 BST.