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O'Cathail, S. M. , Wu, C.-H., Thomas, R., Hawkins, M. A., Maughan, T. S. and Lewis, A. (2021) NRF2 mediates therapeutic resistance to chemoradiation in colorectal cancer through a metabolic switch. Antioxidants, 10(9), 1380. (doi: 10.3390/antiox10091380)

Paterson, K., Zanivan, S. , Glasspool, R., Coffelt, S.B. and Zagnoni, M. (2021) Microfluidic technologies for immunotherapy studies on solid tumours. Lab on a Chip, 21(12), pp. 2306-2329. (doi: 10.1039/D0LC01305F) (PMID:34085677) (PMCID:PMC8204114)

Nielsen, S. R. et al. (2021) Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nature Communications, 12, 3414. (doi: 10.1038/s41467-021-23731-7) (PMID:34099731) (PMCID:PMC8184753)

Zarou, M.-M., Vazquez, A. and Helgason, G. V. (2021) Folate metabolism: a re-emerging therapeutic target in haematological cancers. Leukemia, 35(6), pp. 1539-1551. (doi: 10.1038/s41375-021-01189-2) (PMID:33707653)

McFarlane, A. J., Fercoq, F., Coffelt, S. B. and Carlin, L. M. (2021) Neutrophil dynamics in the tumor microenvironment. Journal of Clinical Investigation, 131(6), e143759. (doi: 10.1172/JCI143759) (PMID:33720040)

Nacke, M. et al. (2021) An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism. Nature Communications, 12, 1623. (doi: 10.1038/s41467-021-21847-4) (PMID:33712589) (PMCID:PMC7955138)

Swaminathan, K., Campbell, A., Papalazarou, V., Jaber-Hijazi, F. , Nixon, C., McGhee, E., Strathdee, D., Sansom, O. J. and Machesky, L. M. (2021) The RAC1 target NCKAP1 plays a crucial role in the progression of Braf;Pten-driven melanoma in mice. Journal of Investigative Dermatology, 141(3), 628-637.e15. (doi: 10.1016/j.jid.2020.06.029) (PMID:32777214)

Alexander, P.G. et al. (2021) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

Latif, A.-L. et al. (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12(1), 241. (doi: 10.1038/s41467-020-20378-8) (PMID:33431824) (PMCID:PMC7801601)

Edwards, S. C., Hoevenaar, W. H.M. and Coffelt, S. B. (2021) Emerging immunotherapies for metastasis. British Journal of Cancer, 124, pp. 37-48. (doi: 10.1038/s41416-020-01160-5) (PMID:33262520)

Smith, T., O'Cathail, S. M. , Silverman, S., Robinson, M., Tsang, Y., Harrison, M. and Hawkins, M. A. (2020) Stereotactic Body Radiotherapy re-irradiation for locally recurrent rectal cancer: outcomes and toxicity. Advances in Radiation Oncology, 5(6), pp. 1311-1319. (doi: 10.1016/j.adro.2020.07.017) (PMID:33305093) (PMCID:PMC7718547)

Suzuki, T., Hayman, L., Kilbey, A., Edwards, J. and Coffelt, S. B. (2020) Gut γδ T cells as guardians, disruptors and instigators of cancer. Immunological Reviews, 298(1), pp. 198-217. (doi: 10.1111/imr.12916) (PMID:32840001)

O'Cathail, S. M. , Smith, T., Owens, R., Zeniou, A., Tsang, Y., Holyoake, D. L.P., Murray, L., Harrison, M. and Hawkins, M. A. (2020) Superior outcomes of nodal metastases compared to visceral sites in oligometastatic colorectal cancer treated with stereotactic ablative radiotherapy. Radiotherapy and Oncology, 151, pp. 280-286. (doi: 10.1016/j.radonc.2020.08.012) (PMID:32866563) (PMCID:PMC7689579)

O'Cathail, S. M. , Wu, C.-H., Lewis, A., Holmes, C., Hawkins, M. A. and Maughan, T. (2020) NRF2 metagene signature is a novel prognostic biomarker in colorectal cancer. Cancer Genetics, 248, pp. 1-10. (doi: 10.1016/j.cancergen.2020.08.006) (PMID:32871287)

Millar, R., Kilbey, A., Remak, S.-J., Severson, T. M., Dhayade, S., Sandilands, E., Foster, K., Bryant, D. M. , Blyth, K. and Coffelt, S. B. (2020) The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer. Molecular Oncology, 14(8), pp. 1868-1880. (doi: 10.1002/1878-0261.12734) (PMID:32484599) (PMCID:PMC7400785)

Muthalagu, N. et al. (2020) Repression of the type I interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in pancreatic ductal adenocarcinoma. Cancer Discovery, 10(6), pp. 872-887. (doi: 10.1158/2159-8290.CD-19-0620) (PMID:32200350) (PMCID:PMC7611248)

Brunton, H. et al. (2020) HNF4A and GATA6 loss reveals therapeutically actionable subtypes in pancreatic cancer. Cell Reports, 31(6), 107625. (doi: 10.1016/j.celrep.2020.107625) (PMID:32402285)

Hari, P. et al. (2019) The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype. Science Advances, 5(6), eaaw0254. (doi: 10.1126/sciadv.aaw0254) (PMID:31183403) (PMCID:PMC6551188)

This list was generated on Mon Oct 18 16:14:52 2021 BST.