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de Araújo, J. S. et al. (2021) A tetrahydrophthalazinone inhibitor of phosphodiesterase with in vitro activity against intracellular trypanosomatids. Antimicrobial Agents and Chemotherapy, 65(3), e00960-20. (doi: 10.1128/AAC.00960-20) (PMID:33361300) (PMCID:PMC8092546)
de Araújo, J. S. et al. (2020) Efficacy of novel pyrazolone phosphodiesterase inhibitors in experimental mouse models of Trypanosoma cruzi. Antimicrobial Agents and Chemotherapy, 64(9), e00414-20. (doi: 10.1128/AAC.00414-20) (PMID:32601163) (PMCID:PMC7449165)
Munday, J. C. et al. (2020) Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages. PLoS Neglected Tropical Diseases, 14(7), e0008447. (doi: 10.1371/journal.pntd.0008447) (PMID:32730343) (PMCID:PMC7430754)
De Araújo, J. S. et al. (2020) Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi. Journal of Antimicrobial Chemotherapy, 75(4), pp. 958-967. (doi: 10.1093/jac/dkz516) (PMID:31860098)
Botros, S. S., El-Lakkany, N. M., Seif el-Din, S. H., William, S., Sabra, A.-N., Hammam, O. A. and De Koning, H. P. (2020) The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo. Experimental Parasitology, 208, 107793. (doi: 10.1016/j.exppara.2019.107793) (PMID:31711973)