Elliott, R. M. (2014) Orthobunyaviruses: recent genetic and structural insights. Nature Reviews Microbiology, 12(10), pp. 673-685. (doi: 10.1038/nrmicro3332)
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Abstract
Orthobunyaviruses, which have small, tripartite, negative-sense RNA genomes and structurally simple virions composed of just four proteins, can have devastating effects on human health and well-being, either by causing disease in humans or by causing disease in livestock and crops. In this Review, I describe the recent genetic and structural advances that have revealed important insights into the composition of orthobunyavirus virions, viral transcription and replication and viral interactions with the host innate immune response. Lastly, I highlight outstanding questions and areas of future research.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Elliott, Professor Richard |
| Authors: | Elliott, R. M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Nature Reviews Microbiology |
| Publisher: | Nature Publishing Group |
| ISSN: | 1740-1526 |
| ISSN (Online): | 1740-1534 |
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