V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: structure and putative function

Shaw, A. M., Bunton, D. C., Fisher, A., McGrath, J. C. , Montgomery, I., Daly, C. and MacDonald, A. (1999) V-shaped cushion at the origin of bovine pulmonary supernumerary arteries: structure and putative function. Journal of Applied Physiology, 87(6), pp. 2348-2356.

Full text not currently available from Enlighten.

Publisher's URL: http://jap.physiology.org/content/87/6/2348

Abstract

This study investigates the anatomic structure at the origin of pulmonary supernumerary arteries and their parent conventional artery. Histological examination showed that at the origin of each supernumerary artery the wall of the parent conventional artery is organized into a distinct V-shaped structure, which begins on the hilum side of each supernumerary artery as a funnel-shaped channel running into the supernumerary artery. The base of the channel is particularly thin walled. The lateral walls of the channel are composed of musculoelastic cushions that become more pronounced toward the supernumerary artery and fuse on its distal side, forming a baffle that projects over the supernumerary artery lumen. These V-shaped structures/cushions were observed with video stereo dissecting microscopy in both an open and closed state in isolated arteries in vitro. Pulmonary vasoconstriction of isolated arteries with the thromboxane A(2) mimetic U-46619 increased the number of V-shaped structures in the closed state. These studies indicate the presence of a novel anatomic structure at the origin of pulmonary supernumerary arteries, which may be able to regulate blood flow into the supernumerary artery.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McGrath, Professor John and Daly, Professor Craig
Authors: Shaw, A. M., Bunton, D. C., Fisher, A., McGrath, J. C., Montgomery, I., Daly, C., and MacDonald, A.
College/School:College of Medical Veterinary and Life Sciences > School of Life Sciences
Journal Name:Journal of Applied Physiology
Publisher:American Physiological Society
ISSN:8750-7587
ISSN (Online):1522-1601
Related URLs:

University Staff: Request a correction | Enlighten Editors: Update this record