Dynamics of red blood cells and vesicles in microchannels of oscillating width

Braunmüller, S., Schmid, L. and Franke, T. (2011) Dynamics of red blood cells and vesicles in microchannels of oscillating width. Journal of Physics: Condensed Matter, 23(18), p. 184116. (doi: 10.1088/0953-8984/23/18/184116)

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Publisher's URL: http://dx.doi.org/10.1088/0953-8984/23/18/184116


We have studied the dynamics of red blood cells and fluid lipid vesicles in hydrodynamic flow fields created by microchannels with periodically varying channel width. For red blood cells we find a transition from a regime with oscillating tilt angle and fixed shape to a regime with oscillating shape with increasing flow velocity. We have determined the crossover to occur at a critical ratio Ly/vm≈2.2 × 10 − 3 s with channel width Ly and red blood cell velocity vm. These oscillations are superposed by shape transitions from a discocyte to a slipper shape at low velocities and a slipper to parachute transition at high flow velocities.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Franke, Professor Thomas and Schmid, Mr Lothar
Authors: Braunmüller, S., Schmid, L., and Franke, T.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Journal of Physics: Condensed Matter
Publisher:IOP Publishing
ISSN (Online):1361-648X
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