Implementing Pasteur's vision for rabies elimination: the evidence base and the needed policy actions

Lankester, F., Hampson, K. , Lembo, T. , Palmer, G., Taylor, L. and Cleaveland, S. (2014) Implementing Pasteur's vision for rabies elimination: the evidence base and the needed policy actions. Science, 345(6204), pp. 1562-1564. (doi:10.1126/science.1256306) (PMID:25258065)

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Abstract

It has been 129 years since Louis Pasteur's experimental protocol saved the life of a child mauled by a rabid dog, despite incomplete understanding of the etiology or mechanisms by which the miracle cure worked (1). The disease has since been well understood, and highly effective vaccines are available, yet Pasteur's vision for ridding the world of rabies has not been realized. Rabies remains a threat to half the world's population and kills more than 69,000 people each year, most of them children (2). We discuss the basis for this neglect and present evidence supporting the feasibility of eliminating canine-mediated rabies and the required policy actions.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Lembo, Dr Tiziana and Cleaveland, Professor Sarah and Taylor, Dr Louise and Hampson, Dr Katie
Authors: Lankester, F., Hampson, K., Lembo, T., Palmer, G., Taylor, L., and Cleaveland, S.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Science
Publisher:American Association for the Advancement of Science
ISSN:0036-8075
ISSN (Online):1095-9203
Copyright Holders:Copyright © 2014 American Association for the Advancement of Science
First Published:First published in Science 345(6204):1562-1564
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher.
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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
522631Epidemiological dynamics of rabies in rural Tanzania and impacts on local communitiesSarah CleavelandWellcome Trust (WELLCOME)087393/B/08/ZRI BIODIVERSITY ANIMAL HEALTH & COMPMED
477381Establishing rabies surveillance systems in Southern TanzaniaDaniel HaydonWellcome Trust (WELLCOME)084615/Z/08/ZRI BIODIVERSITY ANIMAL HEALTH & COMPMED
569041Hierarchical epidemiology: the spread and persistence of infectious diseases in complex landscapesKatie HampsonWellcome Trust (WELLCOME)095787/Z/11/ZRI BIODIVERSITY ANIMAL HEALTH & COMPMED