Transmission of IgA and IgG monoclonal antibodies to mucosal fluids following intranasal or parenteral delivery

Falero-Diaz, G., Challacombe, S., Rahman, D., Mistry, M., Douce, G. , Dougan, G., Acosta, A. and Ivanyi, J. (2000) Transmission of IgA and IgG monoclonal antibodies to mucosal fluids following intranasal or parenteral delivery. International Archives of Allergy and Immunology, 122(2), pp. 143-150. (doi: 10.1159/000024370)

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Abstract

Intranasal, rather than parenteral inoculation of mice is required for the efficient delivery of IgA antibodies against respiratory pulmonary pathogens. Interestingly, IgA-secretory component complexing of intranasally applied Mabs did not significantly influence their persistence in the lungs.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Douce, Dr Gillian
Authors: Falero-Diaz, G., Challacombe, S., Rahman, D., Mistry, M., Douce, G., Dougan, G., Acosta, A., and Ivanyi, J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:International Archives of Allergy and Immunology
Publisher:S. Karger AG
ISSN:1018-2438
ISSN (Online):1423-0097

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