Survival in solid cancer patients following intensive care unit admission

Puxty, K. , McLoone, P., Quasim, T. , Kinsella, J. and Morrison, D. (2014) Survival in solid cancer patients following intensive care unit admission. Intensive Care Medicine, 14(10), pp. 1409-1428. (doi:10.1007/s00134-014-3471-9)

Full text not currently available from Enlighten.

Publisher's URL: http://link.springer.com/article/10.1007%2Fs00134-014-3471-9

Abstract

Purpose: One in seven patients admitted to intensive care units (ICU) has a cancer diagnosis but evidence on their expected outcomes after admission has not been synthesised.<p></p> Methods: Systematic literature review of solid cancer adult patients admitted to ICU from 2000 onwards using EMBASE and MEDLINE electronic databases.<p></p> Results: There were 48 papers identified that reported survival in ICU patients with solid cancers. ICU mortality was reported in 35 studies comprising a total sample of 25,339 patients and ranging from 4.5 to 85 %. The average mortality of the distribution of reported mortality rates within ICU was 31.2 % (95 % CI 24.0–39.0 %). Hospital mortality was reported in 31 studies across a total sample of 74,061 patients. The average hospital mortality was 38.2 % (33.8–42.7 %) and ranged from 4.6 to 76.8 %. Poorer physiological score, invasive mechanical ventilation and poor functional status were associated with higher mortality.<p></p> Conclusions: Several factors have been associated with poor survival in ICU cancer patients; however, primary research is still needed to describe outcomes in cancer patients with sufficient case mix and treatment details to be of prognostic value to clinicians.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Quasim, Dr Tara and McLoone, Mr Philip and Kinsella, Professor John and Puxty, Dr Kathryn and Morrison, Dr David
Authors: Puxty, K., McLoone, P., Quasim, T., Kinsella, J., and Morrison, D.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Intensive Care Medicine
Publisher:Springer Berlin Heidelberg
ISSN:0342-4642
ISSN (Online):1432-1238

University Staff: Request a correction | Enlighten Editors: Update this record