Genetics and hypertension: which information for clinical practice

Padmanabhan, S. and Dominiczak, A. F. (2012) Genetics and hypertension: which information for clinical practice. In: Berbari, A. E. and Mancia, G. (eds.) Special Issues in Hypertension. Springer Milan: Milan, pp. 439-452. ISBN 9788847026001 (doi: 10.1007/978-88-470-2601-8_33)

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Essential hypertension is a complex genetic disease determined by multiple biological pathways and influenced by both genetic and environmental factors. The high prevalence of hypertension, with its major impact on morbidity and mortality, results in a significant health and financial burden on the individual and on society. Genetic insights from monogenic syndromes and genome-wide association studies have advanced our understanding of biological pathways underlying interindividual variation in blood pressure. In this chapter, we describe the genetic basis of blood pressure and hypertension with the implications of these in current clinical practice.

Item Type:Book Sections
Glasgow Author(s) Enlighten ID:Padmanabhan, Professor Sandosh and Dominiczak, Professor Anna
Authors: Padmanabhan, S., and Dominiczak, A. F.
Subjects:Q Science > QH Natural history > QH426 Genetics
R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Publisher:Springer Milan
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