Acute phase proteins: a review of their function, behaviour and measurement in chickens

O'Reilly, E.L. and Eckersall, P.D. (2014) Acute phase proteins: a review of their function, behaviour and measurement in chickens. World's Poultry Science Journal, 70(1), pp. 27-44. (doi: 10.1017/S0043933914000038)

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This review brings together and consolidates the large amount of research on acute phase proteins (APPs) that has been undertaken in chickens. Acute phase proteins are secreted from the liver as a result of inflammation or infection that can be measured in plasma. They have been well-characterised in other farm animal species and have been measured in a wide variety of poultry research areas. The acceleration in chicken APP research is in response to increased interest in ways the immune responses of the chicken can be measured and compared during infection or environmental or nutritional changes. All APPs that have been identified and characterised in chickens are described in the following review and their responses during infection discussed. The APPs are tabulated with basal values and classification to provide a comparative and useful reference. The ways APPs can be measured in chickens and the assays available are also described. This review will detail the functions of the positive APPs in chickens and their behaviour during an APR.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Eckersall, Professor David and O'Reilly, Dr Emily
Authors: O'Reilly, E.L., and Eckersall, P.D.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:World's Poultry Science Journal
Publisher:Cambridge University Press
ISSN (Online):1743-4777
Copyright Holders:Copyright © 2014 World's Poultry Science Association
First Published:First published in World's Poultry Science Journal 70(1):27-44
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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