Impairment-based determinants of quality of life after stroke

Ali, M., Fulton, R., Bath, P. and Brady, M. (2013) Impairment-based determinants of quality of life after stroke. In: UK Stroke Forum 2013 Conference, Harrogate International Centre, North Yorkshire, UK, 3-5 Dec 2013, p. 4. (doi: 10.1111/ijs.12213)

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Introduction: Both motor and non-motor consequences of stroke can be debilitating. It is unclear which specific stroke impairments contribute to Quality of Life (QoL). We explored the relationship between motor and non-motor impairments and QoL at 3 months after stroke. Method: We conducted retrospective analyses of pooled clinical trial data from the Virtual International Stroke Trials Archive (VISTA). National Institutes of Health Stroke Scale (NIHSS) items described aphasia, inattention/neglect, sensory and visual impairment. Pure motor stroke was defined as arm and leg weakness, with or without dysarthria or facial palsy, where remaining NIHSS items were scored as normal. Using ordinal logistic regression, adjusting for age, medical history and thrombolysis, we examined the relationship between pure motor stroke versus motor stroke plus other impairments, on the European Quality of Life Score (EQ-5D) at 3 months. Results: We included 1,091 stroke patients; 284 patients with pure motor stroke, and 807 with the following additional impairments: aphasia (n = 78); visual (n = 82); sensory (n = 594); inattention/neglect (n = 53). No patients had aphasia, inattention/neglect, visual or sensory impairment in the absence of motor involvement. Inattention/neglect in addition to motor stroke was associated with poorer QoL (p = 0.009, OR for poorer QoL = 2.1, 95% CI [1.2, 3.6]) when compared to those with pure motor stroke. Presence of other non-motor impairments in addition to motor stroke showed no significant association with poorer QoL.<p></p> Conclusion: The addition of aphasia, visual or sensory impairments to motor stroke did not appear to reduce QoL at 3 months, compared to those with pure motor stroke.

Item Type:Conference Proceedings
Glasgow Author(s) Enlighten ID:Macisaac, Dr Rachael
Authors: Ali, M., Fulton, R., Bath, P., and Brady, M.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health

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