Neurological complications of human immunodeficiency virus infection

Kennedy, P. G.E. (1988) Neurological complications of human immunodeficiency virus infection. Postgraduate Medical Journal, 64(749), pp. 180-187. (doi: 10.1136/pgmj.64.749.180)

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Publisher's URL: http://dx.doi.org/10.1136/pgmj.64.749.180

Abstract

The protean neurological manifestations of human immunodeficiency virus (HIV) infection are reviewed. Both the central nervous system and peripheral nervous system may be affected and many of the complications may occur in individuals with acquired immunodeficiency syndrome (AIDS)-related complex, or who are seropositive for HIV alone as well as those with the established AIDS syndrome. Specific therapy is available for certain of these neurological conditions, but the clinical course in others is untreatable and progressive. Although it seems likely that the pathogenesis of some of these syndromes such as the AIDS-dementia complex are due to the direct effect of HIV on the nervous system, in others the neurological injury probably occurs as a consequence of the immunosuppression which HIV induces, or immune-mediated mechanisms.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Kennedy, Professor Peter
Authors: Kennedy, P. G.E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Postgraduate Medical Journal
Journal Abbr.:Postgrad. Med.Jj.
Publisher:BMJ Group
ISSN:0032-5473
ISSN (Online):1469-0756

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