Pharmacokinetic pharmacogenomics

Alsanosi, S. M. M., Skiffington, C. and Padmanabhan, S. (2014) Pharmacokinetic pharmacogenomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 341-364. ISBN 9780123868831 (doi:10.1016/B978-0-12-386882-4.00017-7)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1016/B978-0-12-386882-4.00017-7

Abstract

Pharmacokinetics (PK) is the branch of pharmacology that deals with the absorption, distribution, and elimination of drugs. Since the 1950s there have been major advances in understanding the genetic basis of the interindividual variability observed in the pharmacokinetics, efficacy, and toxicity of some drugs. Pharmacokinetic pharmacogenetics feature in an increasing number of drug labels approved by the FDA. The main aim of this chapter is to provide a basic introduction to pharmakinetic principles and to summarize the progress in the pharmacogenomics of key pharmacokinetic systems.

Item Type:Book Sections
Status:Published
Glasgow Author(s) Enlighten ID:Padmanabhan, Professor Sandosh
Authors: Alsanosi, S. M. M., Skiffington, C., and Padmanabhan, S.
Subjects:R Medicine > RM Therapeutics. Pharmacology
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Publisher:Academic Press
ISBN:9780123868831
Related URLs:

University Staff: Request a correction | Enlighten Editors: Update this record