A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndrome

Kennedy, P. and Duchen, L. (1985) A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 48(11), pp. 1103-1106. (doi:10.1136/jnnp.48.11.1103)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1136/jnnp.48.11.1103

Abstract

The intermediolateral column neurons in the lateral horns of the grey matter of the thoracic spinal cord were counted in five patients who had died of motor neuron disease, two of the Shy-Drager syndrome and three of other neurological diseases not affecting the spinal cord or roots. The number of intermediolateral column cells in all the motor neuron disease cases was slightly reduced compared with the control cords, this difference being apparent both when the whole thoracic sympathetic outflow was assessed as well as its upper, middle and lower thirds. The difference, however, was not statistically significant. By contrast, in Shy-Drager cases there was a highly significant reduction in intermediolateral column cells compared with the normal cords.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Kennedy, Professor Peter
Authors: Kennedy, P., and Duchen, L.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Neurology, Neurosurgery and Psychiatry
Publisher:BMJ Publishing Group
ISSN:0022-3050
ISSN (Online):1468-330X

University Staff: Request a correction | Enlighten Editors: Update this record