Parvovirus-derived endogenous viral elements in two South American rodent genomes

Arriagada, G. and Gifford, R. J. (2014) Parvovirus-derived endogenous viral elements in two South American rodent genomes. Journal of Virology, 89(20), pp. 12158-12162. (doi: 10.1128/JVI.01173-14) (PMID:25078696)

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We describe endogenous viral elements (EVEs) derived from parvoviruses (family <i>Parvoviridae</i>) in the long-tailed chinchilla (<i>Chinchilla lanigera</i>) and degu (<i>Octodon degus</i>) genomes. The novel EVEs include Dependovirus-related elements, and representatives of a clearly distinct parvovirus lineage that also has endogenous representatives in marsupial genomes. In the degu, one dependovirus-derived EVEs was found to encode an intact reading frame, and was differentially expressed <i>in vivo</i>, with increased expression in the liver.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Gifford, Dr Robert
Authors: Arriagada, G., and Gifford, R. J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Virology
Journal Abbr.:J. Virol.
Publisher:American Society for Microbiology
ISSN (Online):1098-5514
Copyright Holders:Copyright © 2014 John Wiley and Sons Ltd.
First Published:First published in Journal of Virology 89(20):12158-12162
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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