HIV status, breastfeeding modality at 5 months and postpartum maternal weight changes over 24 months in rural South Africa

Chetty, T., Carter, R. J., Bland, R. M. and Newell, M.-L. (2014) HIV status, breastfeeding modality at 5 months and postpartum maternal weight changes over 24 months in rural South Africa. Tropical Medicine and International Health, 19(7), pp. 852-862. (doi: 10.1111/tmi.12320)

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Abstract

Objective: To determine the effect of infant feeding practices on postpartum weight change among HIV-infected and -uninfected women in South Africa.<p></p> Methods: In a non-randomised intervention cohort study of antiretroviral therapy-naïve women in South Africa, infants were classified as exclusive (EBF), mixed (MF) or non-breastfed (NBF) at each visit. We analysed infant feeding cumulatively from birth to 5 months using 24-hour feeding history (collected weekly for each of the preceding 7 days). Using generalised estimating equation mixed models, allowing for repeated measures, we compared postpartum weight change (kg) from the first maternal postpartum weight within the first 6 weeks (baseline weight) to each subsequent visit through 24 months among 2340 HIV-infected and -uninfected women with live births and at least two postpartum weight measurements.<p></p> Results: HIV-infected (−0.2 kg CI: −1.7 to 1.3 kg; P = 0.81) and -uninfected women (−0.5 kg; 95% CI: −2.1 to 1.2 kg; P = 0.58) had marginal non-significant weight loss from baseline to 24 months postpartum. Adjusting for HIV status, socio-demographic, pregnancy-related and infant factors, 5-month feeding modality was not significantly associated with postpartum weight change: weight change by 24 months postpartum, compared to the change in the reference EBF group, was 0.03 kg in NBF (95% CI: −2.5 to +2.5 kg; P = 0.90) and 0.1 kg in MF (95% CI: −3.0 to +3.2 kg; P = 0.78).<p></p> Conclusion: HIV-infected and -uninfected women experienced similar weight loss over 24 months. Weight change postpartum was not associated with 5-month breastfeeding modality among HIV-infected and -uninfected women.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Bland, Dr Ruth
Authors: Chetty, T., Carter, R. J., Bland, R. M., and Newell, M.-L.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Tropical Medicine and International Health
Publisher:John Wiley & Sons Ltd.
ISSN:1360-2276
ISSN (Online):1365-3156
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Tropical Medicine and International Health 19(7):852-862
Publisher Policy:Reproduced under a Creative Commons License
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