Development of the human fetal testis

O'Shaughnessy, P. J. and Fowler, P. A. (2014) Development of the human fetal testis. Annales d'Endocrinologie, 75(2), pp. 48-53. (doi: 10.1016/j.ando.2014.03.009)

Full text not currently available from Enlighten.

Abstract

Masculinisation and adult fertility in the male are dependent on appropriate fetal endocrine programming. There is also now increasing evidence to indicate that the same mechanisms which regulate masculinisation also affect the general wellbeing of males throughout their life and, particularly, during ageing. Testosterone, secreted by the fetal testes, is the main factor regulating these processes and an understanding of fetal testis development in the human male is essential if we are to prevent adult reproductive disorders. This review focuses on what is known about human testis development and describes the effects of maternal smoking, a surrogate of possible xenotoxicant exposure on fetal testis and fetal liver function.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:O'Shaughnessy, Professor Peter
Authors: O'Shaughnessy, P. J., and Fowler, P. A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Annales d'Endocrinologie
Publisher:Elsevier Masson
ISSN:0003-4266
ISSN (Online):2213-3941

University Staff: Request a correction | Enlighten Editors: Update this record