The effect of kyphoscoliosis on intervertebral disc degeneration in dogs

Faller, K., Penderis, J., Stalin, C. , Guevar, J., Yeamans, C. and Gutierrez Quintana, R. (2014) The effect of kyphoscoliosis on intervertebral disc degeneration in dogs. Veterinary Journal, 200(3), pp. 449-451. (doi:10.1016/j.tvjl.2014.03.027) (PMID:24745767)

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Abstract

In people, abnormalities in vertebral column conformation, such as kyphoscoliosis, induce degenerative changes in adjacent intervertebral disc (IVD) structure and composition. It was hypothesised that canine IVDs adjacent to a vertebral malformation undergo early degeneration.<p></p> In a blinded retrospective study, thoracic IVD degeneration was evaluated in 14 dogs on magnetic resonance images using Pfirrmann's grade. IVDs adjacent to a vertebral malformation had higher grades of degeneration than non-adjacent IVDs (P <0.0001). There was an age-dependency, with dogs between 1 and 4 years showing higher grade of degeneration in adjacent than non-adjacent IVDs (P < 0.0001). Conversely, in older dogs, all IVDs – including the non-adjacents – showed degenerative signs, possibly due to normal aging. These results suggest that congenital vertebral malformation results in early degeneration of adjacent IVDs.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Penderis, Professor Jacques and Guevar, Mr Julien and Faller, Ms Kiterie and Stalin, Mrs Catherine and Gutierrez Quintana, Mr Rodrigo
Authors: Faller, K., Penderis, J., Stalin, C., Guevar, J., Yeamans, C., and Gutierrez Quintana, R.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Veterinary Journal
Publisher:Elsevier
ISSN:1090-0233
ISSN (Online):1532-2971
Published Online:31 March 2014

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