Silanization of glass in the making of ion-sensitive microelectrodes

Munoz, J.-L., Deyhimi, F. and Coles, J.A. (1983) Silanization of glass in the making of ion-sensitive microelectrodes. Journal of Neuroscience Methods, 8(3), pp. 231-247. (doi: 10.1016/0165-0270(83)90037-7)

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The silanization of glass, particularly Pyrex, was studied using reaction conditions that might be applied in the fabrication of ion-sensitive microelectrodes of the liquid-membrane type. The efficacy was tested by measuring the hydrophobicity (contact angle) or electrical resistivity of the treated surface. Aminosilanes, such as trimethyl-(dimethylamino)-silane are better than chlorosilanes, the optimum temperature is 250–330°C, and the reaction comes near to completion in 5 min. Silanization of glass that is newly exposed (as in the pulling of a micropipette) is greatly improved if the surface is treated with acid. There is considerable variation from one kind of glass to another. A recipe for making double-barrelled ion-sensitive microelectrodes is given.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Coles, Dr Jonathan
Authors: Munoz, J.-L., Deyhimi, F., and Coles, J.A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Neuroscience Methods
ISSN (Online):1872-678X

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