Coles, J. A. (1988) Bias current modifies the selectivity of liquid membrane ion-selective microelectrodes. Pflügers Archiv - European Journal of Physiology, 411(3), pp. 339-344. (doi: 10.1007/BF00585125)
Full text not currently available from Enlighten.
Publisher's URL: http://dx.doi.org/10.1007/BF00585125
Abstract
A negative bias potential of up to −8- mV applied to the back of a liquid membrane ion-selective microelectrode containing classical “K+” ion-exchanger was found to make it more selective for millimolar concentrations of K+ over micromolar concentrations of choline, tetramethylammonium, tetraethylammonium and 5-hydroxytryptamine. Conversely, positive bias potential increased severalfold the sensitivity to micromolar concentrations of these ions while decreasing the sensitivity to K+. An increase in response amplitude for millimolar changes of ion concentration was also observed in neutral carrier electrodes for Na+, K+ and Ca2+ with negative bias potential. The various ions caused the resistances of the electrodes to change; these resistance changes contributed to the changes in response amplitude, but there were additional, unexplained, factors. The phenomenon was used to test if the signal from a K+ ion-exchanger microelectrode in extracellular space in bee retina was contaminated by substances other than K+.
Item Type: | Articles |
---|---|
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Coles, Dr Jonathan |
Authors: | Coles, J. A. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Pflügers Archiv - European Journal of Physiology |
Publisher: | Springer Verlag |
ISSN: | 0031-6768 |
ISSN (Online): | 1432-2013 |
University Staff: Request a correction | Enlighten Editors: Update this record