New Multivalent Dendrimer Comprising at Dendrimer Periphery a Number of Active Compounds that are Coupled to the Dendrimer Through 1,2,3-Triazole Or 1,2-Oxazole Heterocyclic Bridge, Useful For Treating, E.G. Cancer

University of Utrecht Holding B.V.; Liskamp R M J; Rijkers D T S; Pieters R J (2008) New Multivalent Dendrimer Comprising at Dendrimer Periphery a Number of Active Compounds that are Coupled to the Dendrimer Through 1,2,3-Triazole Or 1,2-Oxazole Heterocyclic Bridge, Useful For Treating, E.G. Cancer. .

Abstract

The present invention relates to dendrimers being multivalently substituted with active groups, as well as to processes for the preparation thereof and to the use of such multivalent dendrimers. The active compounds encompass peptides, including oligopeptides up to entire proteins, carbohydrates and pharmaceutically active drug molecules.

• Item Type: Patents
• Additional Information: Patent Number: EP1733742-A1; WO2006135233-A1; EP1896079-A1; US2008312344-A1
• Status: Published
• Glasgow Author(s) Enlighten ID: Liskamp, Professor Robert
• Authors: Liskamp, R.M.J., Rijkers, D.T.S., Pieters, R.J., Brouwer, A.J., and Joosten, J.A.F.
• College/School: College of Science and Engineering > School of Chemistry