Cobb, S.R. and Davies, C.H. (2005) Cholinergic modulation of hippocampal cells and circuits. Journal of Physiology, 562(1), pp. 81-88. (doi: 10.1113/jphysiol.2004.076539)
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Publisher's URL: http://dx.doi.org/10.1113/jphysiol.2004.076539
Abstract
Septo-hippocampal cholinergic fibres ramify extensively throughout the hippocampal formation to release acetylcholine upon a diverse range of muscarinic and nicotinic acetylcholine receptors that are differentially expressed by distinct populations of neurones. The resultant modulation of cellular excitability and synaptic transmission within hippocampal circuits underlies the ability of acetylcholine to influence the dynamic properties of the hippocampal network and results in the emergence of a range of stable oscillatory network states. Recent findings suggest a multitude of actions contribute to the oscillogenic properties of acetylcholine which are principally induced by activation of muscarinic receptors but also regulated through activation of nicotinic receptor subtypes.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Cobb, Dr Stuart |
Authors: | Cobb, S.R., and Davies, C.H. |
College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
Journal Name: | Journal of Physiology |
ISSN: | 0022-3751 |
ISSN (Online): | 1469-7793 |
Published Online: | 04 November 2004 |
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