Assembling evidence for identifying reservoirs of infection

Viana, M. , Mancy, R., Biek, R. , Cleaveland, S. , Cross, P. C., Lloyd-Smith, J. O. and Haydon, D. T. (2014) Assembling evidence for identifying reservoirs of infection. Trends in Ecology and Evolution, 29(5), pp. 270-279. (doi:10.1016/j.tree.2014.03.002) (PMID:24726345) (PMCID:PMC4007595)

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Abstract

Many pathogens persist in multihost systems, making the identification of infection reservoirs crucial for devising effective interventions. Here, we present a conceptual framework for classifying patterns of incidence and prevalence, and review recent scientific advances that allow us to study and manage reservoirs simultaneously. We argue that interventions can have a crucial role in enriching our mechanistic understanding of how reservoirs function and should be embedded as quasi-experimental studies in adaptive management frameworks. Single approaches to the study of reservoirs are unlikely to generate conclusive insights whereas the formal integration of data and methodologies, involving interventions, pathogen genetics, and contemporary surveillance techniques, promises to open up new opportunities to advance understanding of complex multihost systems.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Haydon, Professor Daniel and Cleaveland, Professor Sarah and Viana, Dr Mafalda and Mancy, Dr Rebecca and Biek, Dr Roman
Authors: Viana, M., Mancy, R., Biek, R., Cleaveland, S., Cross, P. C., Lloyd-Smith, J. O., and Haydon, D. T.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
College of Social Sciences > School of Education > Interdisciplinary Science Education Technologies and Learning
Journal Name:Trends in Ecology and Evolution
Publisher:Elsevier
ISSN:0169-5347
ISSN (Online):1872-8383
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Trends in Ecology and Evolution 29(5)@270-279
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
518811Towards the strategic control of foot-and-mouth disease in Africa: new techniques for a neglected problemSarah CleavelandBiotechnology and Biological Sciences Research Council (BBSRC)BB/H009302/1RI BIODIVERSITY ANIMAL HEALTH & COMPMED
568221Impact, ecology and social determinants of bacterial zoonoses in northern TanzaniaSarah CleavelandBiotechnology and Biological Sciences Research Council (BBSRC)BB/J010367/1RI BIODIVERSITY ANIMAL HEALTH & COMPMED