Proteomics in veterinary medicine: applications and trends in disease pathogenesis and diagnostics

Ceciliani, F., Eckersall, D. , Burchmore, R. and Lecchi, C. (2014) Proteomics in veterinary medicine: applications and trends in disease pathogenesis and diagnostics. Veterinary Pathology, 51(2), pp. 351-362. (doi:10.1177/0300985813502819)

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Abstract

Advancement in electrophoresis and mass spectrometry techniques along with the recent progresses in genomics, culminating in bovine and pig genome sequencing, widened the potential application of proteomics in the field of veterinary medicine. The aim of the present review is to provide an in-depth perspective about the application of proteomics to animal disease pathogenesis, as well as its utilization in veterinary diagnostics. After an overview on the various proteomic techniques that are currently applied to veterinary sciences, the article focuses on proteomic approaches to animal disease pathogenesis. Included as well are recent achievements in immunoproteomics (ie, the identifications through proteomic techniques of antigen involved in immune response) and histoproteomics (ie, the application of proteomics in tissue processed for immunohistochemistry). Finally, the article focuses on clinical proteomics (ie, the application of proteomics to the identification of new biomarkers of animal diseases).

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Burchmore, Dr Richard and Eckersall, Professor Peter
Authors: Ceciliani, F., Eckersall, D., Burchmore, R., and Lecchi, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Veterinary Pathology
Publisher:SAGE Publications
ISSN:0300-9858
ISSN (Online):1544-2217

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