Emerging phleboviruses

Elliott, R. M. and Brennan, B. (2014) Emerging phleboviruses. Current Opinion in Virology, 5, pp. 50-57. (doi:10.1016/j.coviro.2014.01.011)

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Publisher's URL: http://dx.doi.org/10.1016/j.coviro.2014.01.011

Abstract

The <i>Bunyavidae</i> family is the largest grouping of RNA viruses and arguably the most diverse. Bunyaviruses have a truly global distribution and can infect vertebrates, invertebrates and plants. The majority of bunyaviruses are vectored by arthropods and thus have the remarkable capability to replicate in hosts of disparate phylogeny. The family has provided many examples of emerging viruses including Sin Nombre and related viruses responsible for hantavirus cardiopulmonary syndrome in the Americas, first identified in 1993, and Schmallenberg virus which emerged in Europe in 2011, causing foetal malformations in ruminants. In addition, some well-known bunyaviruses like Rift Valley fever and Crimean-Congo haemorrhagic fever viruses continue to emerge in new geographical locations. In this short review we focus on newly identified viruses associated with severe haemorrhagic disease in humans in China and the US.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Elliott, Professor Richard and Brennan, Dr Benjamin
Authors: Elliott, R. M., and Brennan, B.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Current Opinion in Virology
Publisher:Elsevier
ISSN:1879-6257
ISSN (Online):1879-6265
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Current Opinion in Virology 5:50-57
Publisher Policy:Reproduced under a Creative Commons License
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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
635361Molecular analyses of arbovirus-host interactionsRichard ElliottWellcome Trust (WELLCOME)099220/B/12/ZMVLS III - CENTRE FOR VIRUS RESEARCH
635351Structural and functional analyses of the bunyavirus ribonuceloprotein complexRichard ElliottWellcome Trust (WELLCOME)091783/C/10/ZMVLS III - CENTRE FOR VIRUS RESEARCH