The concise guide to PHARMACOLOGY 2013/14: overview

Alexander, S.P.H., Benson, H.E., Faccenda, E., Pawson, A.J., Sharman, J.L., McGrath, J.C. , Catterall, W.A., Spedding, M., Peters, J.A. and Harmar, A.J. (2013) The concise guide to PHARMACOLOGY 2013/14: overview. British Journal of Pharmacology, 170(8), pp. 1449-1458. (doi: 10.1111/bph.12444)

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Abstract

The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands, which provides more detailed views of target and ligand properties from the IUPHAR database. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.<p></p> It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.<p></p>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McGrath, Professor John
Authors: Alexander, S.P.H., Benson, H.E., Faccenda, E., Pawson, A.J., Sharman, J.L., McGrath, J.C., Catterall, W.A., Spedding, M., Peters, J.A., and Harmar, A.J.
College/School:College of Medical Veterinary and Life Sciences > School of Life Sciences
Journal Name:British Journal of Pharmacology
ISSN:0007-1188
ISSN (Online):1476-5381

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