Screening, intervention and outcome in autism and other developmental disorders: the role of randomized controlled trials

Fernell, E., Wilson, P., Hadjikhani, N., Bourgeron, T., Neville, B., Taylor, D., Minnis, H. and Gillberg, C. (2014) Screening, intervention and outcome in autism and other developmental disorders: the role of randomized controlled trials. Journal of Autism and Developmental Disorders, 44(8), pp. 2074-2076. (doi:10.1007/s10803-014-2070-5) (PMID:24554162)

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Abstract

We draw attention to a number of important considerations in the arguments about screening and outcome of intervention in children with autism and other developmental disorders. Autism screening in itself never provides a final clinical diagnosis, but may well identify developmental deviations indicative of autism—or of other developmental disorders—that should lead to referral for further clinical assessment. Decisions regarding population or clinic screening cannot be allowed to be based on the fact that prospective longitudinal RCT designs over decades could never be performed in complex developmental disorders. We propose an alternative approach. Early screening for autism and other developmental disorders is likely to be of high societal importance and should be promoted and rigorously evaluated.

Item Type:Articles
Additional Information:The final publication is available at Springer via http://dx.doi.org/10.1007/s10803-014-2070-5
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gillberg, Professor Christopher and Minnis, Professor Helen
Authors: Fernell, E., Wilson, P., Hadjikhani, N., Bourgeron, T., Neville, B., Taylor, D., Minnis, H., and Gillberg, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Mental Health and Wellbeing
Journal Name:Journal of Autism and Developmental Disorders
ISSN:0162-3257
ISSN (Online):1573-3432
Copyright Holders:Copyright © 2014 Springer
First Published:First published in Journal of Autism and Developmental Disorders 44(8):2074-2076
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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