Hamvas, R.M.J., Johnson, M., Vlieger, A.M., Ling, C., Sherriff, A. , Wade, A., Klein, N.J., Turner, M.W. and Webster, A.D.B. (2005) Role for mannose binding lectin in the prevention of mycoplasma infection. Infection and Immunity, 73(8), pp. 5238-5240. (doi: 10.1128/IAI.73.8.5238-5240.2005)
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Publisher's URL: http://dx.doi.org/10.1128/IAI.73.8.5238-5240.2005
Abstract
Polymorphisms in exon 1 of the MBL-2 gene, resulting in reduced plasma levels of mannose binding lectin, were significantly overrepresented in 23 patients with primary antibody deficiency and culture-proven mycoplasma infections (P = 0.0038). This association persisted with the inclusion of a further nine suspected (doxycycline-responsive) cases (P = 0.0087). The lectin was shown to bind to three strains of mycoplasma.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Sherriff, Professor Andrea |
| Authors: | Hamvas, R.M.J., Johnson, M., Vlieger, A.M., Ling, C., Sherriff, A., Wade, A., Klein, N.J., Turner, M.W., and Webster, A.D.B. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School |
| Journal Name: | Infection and Immunity |
| Journal Abbr.: | IAI |
| Publisher: | American Society for Microbiology |
| ISSN: | 0019-9567 |
| ISSN (Online): | 1098-5522 |
| Related URLs: |
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