Disease associated malnutrition correlates with length of hospital stay in children

Hecht, C. et al. (2014) Disease associated malnutrition correlates with length of hospital stay in children. Clinical Nutrition, 34(1), pp. 53-59. (doi:10.1016/j.clnu.2014.01.003)

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Abstract

Background & aims: Previous studies reported a wide range of estimated malnutrition prevalence (6–30%) in paediatric inpatients based on various anthropometric criteria. We performed anthropometry in hospitalised children and assessed the relationship between malnutrition and length of hospital stay (LOS) and complication rates.<p></p> Methods: In a prospective multi-centre European study, 2567 patients aged 1 month to 18 years were assessed in 14 centres in 12 countries by standardised anthropometry within the first 24 h after admission. Body mass index (BMI) and height/length <−2 standard deviation scores (SDS, WHO reference) were related to LOS (primary outcome), frequency of gastrointestinal (diarrhoea and vomiting) and infectious complications (antibiotic use), weight change during stay (secondary outcomes) and quality of life.<p></p> Results: A BMI <−2 SDS was present in 7.0% of the patients at hospital admission (range 4.0–9.3% across countries) with a higher prevalence in infants (10.8%) and toddlers aged 1–2 years (8.3%). A BMI <−2 to ≥−3 SDS (moderate malnutrition) and a BMI <−3 SDS (severe malnutrition) was associated with a 1.3 (CI95: 1.01, 1.55) and 1.6 (CI95: 1.27, 2.10) days longer LOS, respectively (p = 0.04 and p < 0.001). Reduced BMI <−2 SDS was also associated to lower quality of life, and more frequent occurrence of diarrhoea (22% vs 12%, p < 0.001) and vomiting (26% vs 14%, p < 0.001).<p></p> Conclusion: Disease associated malnutrition in hospitalised children in Europe is common and is associated with significantly prolonged LOS and increased complications, with possible major cost implications, and reduced quality of life.<p></p>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Flynn, Dr Diane and Gerasimidis, Dr Konstantinos
Authors: Hecht, C., Weber, M., Grote, V., Daskalou, E., Dell'Era, L., Flynn, D., Gerasimidis, K., Gottrand, F., Hartman, C., Hulst, J., Joosten, K., Karagiozoglou-Lampoudi, T., Koetse, H. A., Kolaček, S., Książyk, J., Niseteo, T., Olszewska, K., Pavesi, P., Piwowarczyk, A., Rousseaux, J., Shamir, R., Sullivan, P. B., Szajewska, H., Vernon-Roberts, A., and Koletzko, B.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Clinical Nutrition
Publisher:Elsevier
ISSN:0261-5614
ISSN (Online):1532-1983

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