Modeling human liver biology using stem cell-derived hepatocytes

Sun, P., Zhou, X., Farnworth, S., Patel, A. and Hay, D. (2013) Modeling human liver biology using stem cell-derived hepatocytes. International Journal of Molecular Sciences, 14(11), pp. 22011-22021. (doi:10.3390/ijms141122011) (PMID:24201130) (PMCID:PMC3856048)

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Abstract

Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Sun, Dr Ping Nan and Patel, Professor Arvind and Zhou, Dr Xiaoling
Authors: Sun, P., Zhou, X., Farnworth, S., Patel, A., and Hay, D.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:International Journal of Molecular Sciences
Journal Abbr.:Int. J. Mol. Sci.
Publisher:M D P I AG
ISSN:1661-6596
ISSN (Online):1422-0067
Copyright Holders:Copyright © 2013 The Authors
First Published:First published in International Journal of Molecular Sciences 14(11):22011-22021
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
633481Development of Novel in Vitro Models for Hepatitus B virus and Hepatitus C virus Infection and ReplicationArvind PatelMedical Research Council (MRC)MR/K008757/1III - CENTRE FOR VIRUS RESEARCH
656491Basis of the host range and tissue tropism for hepatitis C virusArvind PatelMedical Research Council (MRC)MC_UU_12014/2MVLS III - CENTRE FOR VIRUS RESEARCH