Pituitary metastasis of pancreatic origin in a dog presenting with acute-onset blindness

Gutierrez Quintana, R., Carrera, I., Dobromylskyj, M., Patterson-Kane, J., Ortega, M. and Wessmann, A. (2013) Pituitary metastasis of pancreatic origin in a dog presenting with acute-onset blindness. Journal of the American Animal Hospital Association, 49(6), pp. 403-406. (doi:10.5326/JAAHA-MS-5926) (PMID:24051261)

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Abstract

Pituitary metastases have rarely been recorded in dogs, and to date, none of those reported have been of pancreatic origin. MRI findings are available for only one of those cases. Herein the authors present an 11 yr old English springer spaniel diagnosed with pituitary metastasis of pancreatic origin with a 24 hr history of blindness and only a single lesion on MRI. Neurologic and ophthalmologic examinations localized the lesion to the optic nerves, optic tracts, or optic chiasm. MRI showed a single lesion characterized by a well-circumscribed pituitary mass with extrasellar extension, causing compression of the optic chiasm. Signal intensity was unusual as enhancement could not be appreciated after contrast administration. The dog was euthanized without further diagnostic tests. Histopathologic examination revealed a poorly differentiated exocrine pancreatic carcinoma with widespread metastasis involving the pituitary gland. To the authors’ knowledge, this is the first such case reported in a dog. Pituitary metastases should be included as a differential diagnosis for dogs presenting with acute-onset blindness and for single brain masses affecting the pituitary gland.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Carrera, Miss Inez and Wessmann, Dr Annette and Patterson-Kane, Professor Janet and Ortega, Miss Maria and Gutierrez Quintana, Mr Rodrigo
Authors: Gutierrez Quintana, R., Carrera, I., Dobromylskyj, M., Patterson-Kane, J., Ortega, M., and Wessmann, A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Journal of the American Animal Hospital Association
ISSN:0587-2871
ISSN (Online):1547-3317

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