Systolic hypertension in pregnancy and cardiovascular mortality: a 44-Year follow-up study

Luoto, R., Kharazmi, E., Whitley, E. , Raitanen, J., Gissler, M. and Hemminki, E. (2008) Systolic hypertension in pregnancy and cardiovascular mortality: a 44-Year follow-up study. Hypertension in Pregnancy, 27(1), pp. 87-94. (doi: 10.1080/10641950701826810)

Abstract

Objective: To assess role of systolic hypertension during pregnancy in long-term mortality. Method: A total of 4,090 Finnish women who delivered in the period from 1954 to 1963 were followed up for an average of 44 years. Mortality data were obtained from the Finnish cause-of-death registry. Cox-proportional hazard models were used for analysis. Results: Cardiovascular mortality was significantly higher among women with systolic hypertension in early or late pregnancy. Women with systolic hypertension in early pregnancy without proteinuria had a significantly increased risk for cardiovascular death. Primiparas with systolic hypertension and proteinuria had a higher risk for cardiovascular death. Conclusion: By considering women with systolic hypertension in pregnancy as being at higher risk for cardiovascular diseases, there may be an opportunity to prevent untimely mortality.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Whitley, Dr Elise
• Authors: Luoto, R., Kharazmi, E., Whitley, E., Raitanen, J., Gissler, M., and Hemminki, E.
• College/School: College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > MRC/CSO SPHSU
• Journal Name: Hypertension in Pregnancy
• ISSN: 1064-1955
• ISSN (Online): 1525-6065