Adenosine A2 receptors on human monocytes modulate C2 production

Lappin, D. and Whaley, K. (1984) Adenosine A2 receptors on human monocytes modulate C2 production. Clinical and Experimental Immunology, 57(2), pp. 454-460.

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Adenosine inhibits C2 production by human monocytes. The use of synthetic analogues of adenosine suggested that the action was mediated by receptors of A2 type. EHNA which inhibits the enzyme adenosine deaminase and increases the concentration of intracellular adenosine also reduces C2 production. It is therefore possible that endogenous adenosine regulates C2 synthesis.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Lappin, Dr David
Authors: Lappin, D., and Whaley, K.
Subjects:Q Science > QR Microbiology > QR180 Immunology
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
Journal Name:Clinical and Experimental Immunology
Publisher:Wiley-Blackwell Publishing Ltd.
ISSN (Online):1365-2249
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