Wilson, S.J. , Webb, B.L.J., Maplanka, C., Newman, R.M., Verschoor, E.J., Heeney, J.L. and Towers, G.J. (2008) Rhesus macaque TRIM5 alleles have divergent antiretroviral specificities. Journal of Virology, 82(14), pp. 7243-7247. (doi: 10.1128/JVI.00307-08)
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Abstract
TRIM5alpha is a potent barrier to cross-species retroviral transmission, and TRIM5alphas from different species have divergent antiretroviral specificities. Multiple TRIM5 alleles circulate within rhesus macaque populations. Here we show that they too have different antiretroviral specificities, highlighting how TRIM5 genotypes contribute to protection in an individual or a population.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Wilson, Professor Sam |
| Authors: | Wilson, S.J., Webb, B.L.J., Maplanka, C., Newman, R.M., Verschoor, E.J., Heeney, J.L., and Towers, G.J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Journal of Virology |
| ISSN: | 0022-538X |
| ISSN (Online): | 1098-5514 |
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