Gender- and age-related differences in clinical presentation and management of outpatients with stable coronary artery disease

Ferrari, R., Abergel, H., Ford, I. , Fox, K.M., Greenlaw, N., Steg, P.G., Hu, D., Tendera, M. and Tardif, J. (2013) Gender- and age-related differences in clinical presentation and management of outpatients with stable coronary artery disease. International Journal of Cardiology, 167(6), pp. 2938-2943. (doi: 10.1016/j.ijcard.2012.08.013) (PMID:22985742)

[img]
Preview
Text
87061.pdf - Accepted Version

250kB

Abstract

<br>Introduction: Contemporary generalizable data on the demographics and management of outpatients with stable coronary artery disease (CAD) in routine clinical practice are sparse. Using the data from the CLARIFY registry we describe gender- and age-related differences in baseline characteristics and management of these patients across broad geographic regions.</br> <br>Methods: This international, prospective, observational, longitudinal registry enrolled stable CAD outpatients from 45 countries in Africa, Asia, Australia, Europe, the Middle East, and North, Central, and South America.</br> <br>Results: Baseline data were available for 33 280 patients. Mean (SD) age was 64 (10.5) years and 22.5% of patients were female. The prevalence of CAD risk factors was generally higher in women than in men. Women were older (66.6 vs 63.4 years), more frequently diagnosed with diabetes (33% vs 28%), hypertension (79% vs 69%), and higher resting heart rate (69 vs 67 bpm), and were less physically active. Smoking and a history of myocardial infarction were more common in men. Women were more likely to have angina (28% vs 20%), but less likely to have undergone revascularization procedures. CAD was more likely to be asymptomatic in older patients perhaps because of reduced levels of physical activity. Prescription of evidence-based medication for secondary prevention varied with age, with patients ≥ 75 years treated less often with beta blockers, aspirin and angiotensin-converting enzyme inhibitors than patients < 65 years.</br> <br>Conclusions: Important gender-related differences in clinical characteristics and management continue to exist in all age groups of outpatients with stable CAD.</br>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Greenlaw, Miss Nicola and Ford, Professor Ian
Authors: Ferrari, R., Abergel, H., Ford, I., Fox, K.M., Greenlaw, N., Steg, P.G., Hu, D., Tendera, M., and Tardif, J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
Journal Name:International Journal of Cardiology
Publisher:Elsevier
ISSN:0167-5273
ISSN (Online):1874-1754
Copyright Holders:Copyright © 2012 Elsevier
First Published:First published in International Journal of Cardiology 167(6):2938-2943
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

University Staff: Request a correction | Enlighten Editors: Update this record