Protein trafficking inside Toxoplasma gondii

Sheiner, L. and Soldati-Favre, D. (2008) Protein trafficking inside Toxoplasma gondii. Traffic, 9(5), pp. 636-646. (doi:10.1111/j.1600-0854.2008.00713.x)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1111/j.1600-0854.2008.00713.x

Abstract

The accurate targeting of proteins to their final destination is an essential process in all living cells. Apicomplexans are obligate intracellular protozoan parasites that possess a compartmental organization similar to that of free-living eukaryotes but can be viewed as professional secretory cells. Establishment of parasitism involves the sequential secretion from highly specialized secretory organelles, including micronemes, rhoptries and dense granules. Additionally, apicomplexans harbor a tubular mitochondrion, a nonphotosynthetic plastid organelle termed the apicoplast, acidocalcisomes and an elaborated inner membrane complex composed of flattened membrane cisternae that are derived from the secretory pathway. Given the multitude of destinations both inside and outside the parasite, the endoplasmic reticulum/Golgi of the apicomplexans constitutes one of the most busy roads intersections in eukaryotic traffic.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Sheiner, Dr Lilach
Authors: Sheiner, L., and Soldati-Favre, D.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Traffic
ISSN:1398-9219
ISSN (Online):1600-0854
Related URLs:

University Staff: Request a correction | Enlighten Editors: Update this record