Detecting mosaic structures in DNA sequence alignments

Husmeier, D. (2006) Detecting mosaic structures in DNA sequence alignments. In: Misra, J.C. (ed.) Biomathematics: Modelling and Simulation. World Scientific: Hackensack, NJ, USA, pp. 1-35. ISBN 9789812381101 (doi: 10.1142/9789812774859_0001)

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This article first provides a concise introduction to the statistical approach to phyloge- netics. It then describes a new method for detecting mosaic structures in DNA sequence alignments, which is based on combining two probabilistic graphical models: (1) a taxon graph (phylogenetic tree) representing the relationships among the taxa, and (2) a site graph (hidden Markov model) representing spatial correlations between nucleotides.

Item Type:Book Sections
Additional Information:iomathematics: Modelling and Simulation, J.C. Misra, Copyright @ 2006 with permission from World Scientific Publishing Co. Pte. Ltd.
Glasgow Author(s) Enlighten ID:Husmeier, Professor Dirk
Authors: Husmeier, D.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Statistics
Publisher:World Scientific
Copyright Holders:Copyright © 2006 World Scientific Publishing Co.
Publisher Policy:Reproduced with the permission of the publisher

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