Non-hormonal management of vasomotor symptoms

Sassarini, J. and Lumsden, M.A. (2013) Non-hormonal management of vasomotor symptoms. Climacteric, 16(S1), pp. 31-36. (doi: 10.3109/13697137.2013.805525)

Abstract

Vasomotor symptoms are the most common indication for the prescription of hormone replacement therapy since it is effective in over 80% of cases. In 1995, 37% of American women took hormone replacement therapy, principally for this purpose. However, following the publication of results from the Women's Health Initiative, as many as half of these women in the US and in the UK and New Zealand discontinued hormone therapy. Discontinuation of estrogen is often accompanied by a return of vasomotor symptoms; however, only a small number (18%) of women report restarting hormone therapy. Alternatives are available, but limited knowledge on etiology and mechanisms of hot flushing represents a major obstacle for the development of new, targeted, non-hormonal treatments, and no current alternatives are as effective as estrogen.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Sassarini, Dr Jenifer and Lumsden, Professor Mary
• Authors: Sassarini, J., and Lumsden, M.A.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Climacteric
• ISSN: 1369-7137
• ISSN (Online): 1473-0804