The clinical importance of fungal biofilms

Ramage, G. and Williams, C. (2013) The clinical importance of fungal biofilms. Advances in Applied Microbiology, 84, pp. 27-83. (doi:10.1016/B978-0-12-407673-0.00002-3)

Ramage, G. and Williams, C. (2013) The clinical importance of fungal biofilms. Advances in Applied Microbiology, 84, pp. 27-83. (doi:10.1016/B978-0-12-407673-0.00002-3)

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Abstract

Fungal biofilms have become an increasingly important clinical problem. The widespread use of antibiotics, frequent use of indwelling medical devices, and a trend toward increased patient immunosuppression have resulted in a creation of opportunity for clinically important yeasts and molds to form biofilms. This review will discuss the diversity and importance of fungal biofilms in the context of clinical medicine, provide novel insights into the clinical management of fungal biofilm infection, present evidence why these structures are recalcitrant to antifungal therapy, and discuss how our knowledge and understanding may lead to novel therapeutic intervention.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ramage, Professor Gordon and Williams, Dr Craig
Authors: Ramage, G., and Williams, C.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
Journal Name:Advances in Applied Microbiology
ISSN:0065-2164

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