Genetic analysis workshop III: Use of multidimensional scaling in chromosome mapping

Donald, J., Sturt, E., Der, G. and McCusker, K. (1985) Genetic analysis workshop III: Use of multidimensional scaling in chromosome mapping. Genetic Epidemiology, 2(2), pp. 207-209. (doi:10.1002/gepi.1370020216)

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Publisher's URL: http://dx.doi.org/10.1002/gepi.1370020216

Abstract

Two-point methods were used throughout. Male and female lod scores were calculated using LIPED. Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. ZLODS estimates recombination fractions. OBM calculates the likelihood and estimates the map distances for a given ordering of loci. Since OBM will only analyze a specified ordering, multidimensional scaling was used as a general method for establishing linkage groups and likely orderings within them.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Der, Mr Geoffrey
Authors: Donald, J., Sturt, E., Der, G., and McCusker, K.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > MRC/CSO Unit
Journal Name:Genetic Epidemiology
ISSN:0741-0395
ISSN (Online):1098-2272

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