Paternal age in relation to offspring intelligence in the West of Scotland twenty-07 prospective cohort study

Whitley, E. , Deary, I.J., Der, G. , Batty, G.D. and Benzeval, M. (2012) Paternal age in relation to offspring intelligence in the West of Scotland twenty-07 prospective cohort study. PLoS ONE, 7(12), e52112. (doi:10.1371/journal.pone.0052112)

Whitley, E. , Deary, I.J., Der, G. , Batty, G.D. and Benzeval, M. (2012) Paternal age in relation to offspring intelligence in the West of Scotland twenty-07 prospective cohort study. PLoS ONE, 7(12), e52112. (doi:10.1371/journal.pone.0052112)

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Abstract

<br>Background: The adverse effects of advancing maternal age on offspring's health and development are well understood. Much less is known about the impact of paternal age.</br> <br>Methods: We explored paternal age-offspring cognition associations in 772 participants from the West of Scotland Twenty-07 study. Offspring cognitive ability was assessed using Part 1 of the Alice Heim 4 (AH4) test of General Intelligence and by reaction time (RT).</br> <br>Results: There was no evidence of a parental age association with offspring RT. However, we observed an inverse U-shaped association between paternal age and offspring AH4 score with the lowest scores observed for the youngest and oldest fathers. Adjustment for parental education and socioeconomic status somewhat attenuated this association. Adjustment for number of, particularly older, siblings further reduced the scores of children of younger fathers and appeared to account for the lower offspring scores in the oldest paternal age group.</br> <br>Conclusion: We observed a paternal age association with AH4 but not RT, a measure of cognition largely independent of social and educational experiences. Factors such as parental education, socioeconomic status and number of, particularly older, siblings may play an important role in accounting for paternal age-AH4 associations. Future studies should include parental intelligence.</br>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Batty, Dr G and Der, Mr Geoffrey and Whitley, Dr Elise and Benzeval, Dr Michaela
Authors: Whitley, E., Deary, I.J., Der, G., Batty, G.D., and Benzeval, M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > MRC/CSO Unit
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
Journal Name:PLoS ONE
Publisher:Public Library of Science
ISSN:1932-6203
ISSN (Online):1932-6203
Copyright Holders:Copyright © 2012 The Authors
First Published:First published in PLoS ONE 7(12):e52112
Publisher Policy:Reproduced under a Creative Commons License

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