Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

Dickens, N.J. et al. (2010) Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome. Clinical Cancer Research, 16(6), pp. 1856-1864. (doi: 10.1158/1078-0432.CCR-09-2831)

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Abstract

We developed a simple 6-gene expression signature from the 97-gene signature that can be used to identify poor-prognosis myeloma in the clinical environment. This signature could form the basis of future trials aimed at improving the outcome of poor-prognosis myeloma.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dickens, Dr Nicholas
Authors: Dickens, N.J., Walker, B.A., Leone, P.E., Johnson, D.C., Brito, J.L., Zeisig, A., Jenner, M.W., Boyd, K.D., Gonzalez, D., Gregory, W.M., Ross, F.M., Davies, F.E., and Morgan, G.J.
Subjects:R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:Clinical Cancer Research
Publisher:American Association for Cancer Research
ISSN:1078-0432
ISSN (Online):1557-3265

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