Initial experience with a dynamic imaging-derived immersed boundary model of human left ventricle

Gao, H. , Griffith, B. E., Carrick, D., McComb, C., Berry, C. and Luo, X. (2013) Initial experience with a dynamic imaging-derived immersed boundary model of human left ventricle. In: Ourselin, S., Rueckert, D. and Xmith, N. (eds.) Functional Imaging and Modeling of the Heart. Series: Lecture notes in computer science, 7945. Springer Berlin Heidelberg: Berlin, Germany, pp. 11-18. ISBN 9783642388989 (doi: 10.1007/978-3-642-38899-6_2)

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Abstract

Understanding the myocardial biomechanics of the left ventricle (LV) in health and disease is important for improving patient risk stratification and management. Computational models of the heart are able to provide insights into the mechanics of heart function. In this study, we develop a dynamic human LV model using an immersed boundary (IB) method along with a finite element description of myocardial mechanics. Our results show that this computational model is able to simulate LV dynamics from end-diastole to end-systole, and that the model results are in reasonably good agreement with noninvasive in vivo strain measurements obtained by magnetic resonance (MR) imaging.

Item Type:Book Sections
Status:Published
Glasgow Author(s) Enlighten ID:Carrick, Dr David and Luo, Professor Xiaoyu and Griffith, Dr Boyce and Gao, Dr Hao and Berry, Professor Colin and McComb, Mr Chris
Authors: Gao, H., Griffith, B. E., Carrick, D., McComb, C., Berry, C., and Luo, X.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Infection & Immunity
College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Publisher:Springer Berlin Heidelberg
ISBN:9783642388989

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