Barr, T.A. and Heath, A.W. (1999) Enhanced in vivo immune responses to bacterial lipopolysaccharide by exogenous CD40 stimulation. Infection and Immunity, 67(7), pp. 3637-3640.
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Publisher's URL: http://iai.asm.org/content/67/7/3637
Abstract
The lack of specific T-cell help in immune responses to thymus-independent antigens results in weak, predominantly immunoglobulin M-mediated immunity with little or no memory. In the work presented here we show how the exogenous stimulation of CD40 by monoclonal antibodies can mimic T-cell help, resulting in enhanced immune responses which are protective against bacterial infection.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Barr, Dr Tom |
| Authors: | Barr, T.A., and Heath, A.W. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Infection and Immunity |
| ISSN: | 0019-9567 |
| Related URLs: |
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