Barr, T.A., Krembuszewski, M., Gupta, M., Gray, D. and Mareque-Rivas, J.C. (2010) Quantum dots decorated with pathogen associated molecular patterns as fluorescent synthetic pathogen models. Molecular BioSystems, 6(9), pp. 1572-1575. (doi: 10.1039/c002066d)
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Abstract
We attached the pathogen associated molecular pattern Kdo2-Lipid A (the lipopolysaccharide (LPS) from Escherichia coli (E. coli)) to QDs by hydrophobic interactions to synthetically mimic the surface of E. coli. QD-LPS conjugates bind, are taken up and activate effectively macrophages in vitro and they have potent immunostimulatory activity in vivo.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Barr, Dr Tom |
| Authors: | Barr, T.A., Krembuszewski, M., Gupta, M., Gray, D., and Mareque-Rivas, J.C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Molecular BioSystems |
| ISSN: | 1742-206X |
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