Quantum dots decorated with pathogen associated molecular patterns as fluorescent synthetic pathogen models

Barr, T.A., Krembuszewski, M., Gupta, M., Gray, D. and Mareque-Rivas, J.C. (2010) Quantum dots decorated with pathogen associated molecular patterns as fluorescent synthetic pathogen models. Molecular BioSystems, 6(9), pp. 1572-1575. (doi:10.1039/c002066d)

Full text not currently available from Enlighten.

Abstract

We attached the pathogen associated molecular pattern Kdo2-Lipid A (the lipopolysaccharide (LPS) from Escherichia coli (E. coli)) to QDs by hydrophobic interactions to synthetically mimic the surface of E. coli. QD-LPS conjugates bind, are taken up and activate effectively macrophages in vitro and they have potent immunostimulatory activity in vivo.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Barr, Dr Tom
Authors: Barr, T.A., Krembuszewski, M., Gupta, M., Gray, D., and Mareque-Rivas, J.C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Molecular BioSystems
ISSN:1742-206X

University Staff: Request a correction | Enlighten Editors: Update this record