Mahmoudi, M., Mercer, J.R. and Bennett, M. (2006) DNA damage and repair in atherosclerosis. Cardiovascular Research, 71(2), pp. 259-268. (doi: 10.1016/j.cardiores.2006.03.002)
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Abstract
There is increasing evidence that human atherosclerosis is associated with damage to the DNA of both circulating cells, and cells of the vessel wall. Reactive oxygen species are the most likely agents inducing DNA damage in atherosclerosis. DNA damage produces a variety of responses, including cell senescence, apoptosis and DNA repair. This review summarises the evidence for DNA damage in atherosclerosis, the cellular responses to damage and the mechanisms of signalling DNA damage.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Mercer, Dr John |
| Authors: | Mahmoudi, M., Mercer, J.R., and Bennett, M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | Cardiovascular Research |
| Journal Abbr.: | Cardiovasc Res |
| ISSN: | 0008-6363 |
| ISSN (Online): | 1755-3245 |
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